| June 18, 2008 |
| Boston Red Sox at Philadelphia Phillies, 1:05 pm |
| (R) Justin Masterson (3-1) vs. (R) Kyle Kendrick (6-2) |
| Detroit Tigers at San Francisco Giants, 3:45 pm |
| (R) Armando Galarraga (6-2) vs. (L) Barry Zito (2-10) |
| Houston Astros at Baltimore Orioles, 7:05 pm |
| (R) Brian Moehler (3-3) vs. (R) Jeremy Guthrie (3-7) |
| San Diego Padres at New York Yankees, 7:05 pm |
| (R) Jake Peavy (5-3) vs. (R) Darrell Rasner (3-4) |
| Chicago Cubs at Tampa Bay Rays, 7:10 pm |
| (R) Carlos Zambrano (8-2) vs. (R) Andy Sonnanstine (7-3) |
| Los Angeles Dodgers at Cincinnati Reds, 7:10 pm |
| (R) Hiroki Kuroda (3-6) vs. (R) Bronson Arroyo (4-5) |
| Atlanta Braves at Texas Rangers, 8:05 pm |
| (L) Jo-Jo Reyes (3-4) vs. (R) Eric Hurley (0-0) |
| Toronto Blue Jays at Milwaukee Brewers, 8:05 pm |
| (R) Shaun Marcum (5-3) vs. (R) Ben Sheets (7-1) |
| Washington Nationals at Minnesota Twins, 8:10 pm |
| (R) Jason Bergmann (1-4) vs. (R) Kevin Slowey (3-6) |
| Pittsburgh Pirates at Chicago White Sox, 8:11 pm |
| (L) Tom Gorzelanny (5-5) vs. (L) Mark Buehrle (3-6) |
| Kansas City Royals at St. Louis Cardinals, 8:15 pm |
| (R) Brian Bannister (5-6) vs. (R) Braden Looper (8-5) |
| Cleveland Indians at Colorado Rockies, 9:05 pm |
| (L) Aaron Laffey (4-3) vs. (L) Jeff Francis (2-6) |
| Oakland Athletics at Arizona Diamondbacks, 9:40 pm |
| (R) Joe Blanton (3-9) vs. (R) Dan Haren (6-4) |
| New York Mets at Anaheim Angels, 10:05 pm |
| (L) Oliver Perez (5-4) vs. (R) Jon Garland (6-4) |
| Florida Marlins at Seattle Mariners, 10:10 pm |
| (R) Ryan Tucker (1-1) vs. (R) R.A. Dickey (1-2) |
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| Probable Starting Pitchers from The Sports Network | | |
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